Abuse his wildcard! I would recommend a Crossgen/Mystic figure and a team ability that has stealth. Have him sit in stealth with someone he can mastermind damage to. R Yukio, R She-Hulk and LE Silver Dreadnought are great choices.
Make sure that he does not take damage because he loses most of his powers after one click.
World's Top 16 - 3 Years in a Row
2010 - 5th Place 2011 - 10th Place
2012 - 11th Place (Winner of 2nd Day Golden Age Event)
Are you sure about the Mystics rule? The damage is still taken by Doom (he was attacked successfully and damage was dealt -- different than if he was successfully attacked and toughness or something reduced the damage)