I just played a 200 point team with her and Johnny Alpha for Stealth+TK. Got her in, she MCed two folks (no feedback due to low point levels), got her out for heals (easy due to low defense value). Rinse, lather, repeat. I didn't win, but I had fun with her.
E Karma picks up a 2nd target and not much else over the R version, but it really makes a difference in raising the stakes of her gameplay. Grabbing two of your opponent's figures will likely wreck their board position much more effectively - for example, pulling one target in and sending the other away and into hindering will let you gang up on your prey. It's often worth the feedback damage... just don't forget to pack Prob Control because you need any MC-influenced attacks to count. Once she drops to an 8 attack, use her TA as a battery for more important pieces.
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